Le travail de thèse vise à modéliser la dynamique spatiale et temporelle d’une maladie à transmission vectorielle comme la dengue, à partir de données environnementales extraites d’images de télédétection.

Un modèle de diffusion, basé sur des données entomologiques et sur des paramètres environnementaux issus d’une image satellitale, est proposé pour décrire la dynamique des moustiques vecteurs de la maladie. (lire la suite…)

Twenty-seven samples of Aedes aegypti (F1 generation) from French Guiana were tested for their susceptibility to dengue serotype 2 virus.

Very high infection rates were observed by indirect fluorescent antibody (IFA) test. Ae. aegypti samples were pooled according to two groups: the first group (N=10) represented mosquitoes from the urbanized area of Cayenne and surroundings, and the second group (N=17) corresponded to mosquitoes collected in the countryside. (lire la suite…)

A serologic survey for Mayaro virus (Alphavirus, Togaviridae) in 28 wild nonflying forest mammal species in French Guiana showed a prevalence ranging from 0% to 52% and increasing with age.

Species active during the day and those who spent time in trees were significantly more infected, results consistent with transmission implicating diurnal mosquitoes and continuous infectious pressure. (lire la suite…)

La mission avait pour but d’une part de contribuer par une expertise collective multidisciplinaire réalisée sur le terrain à l’analyse de la situation épidémique de la dengue en Guyane, et d’autre part d’apporter des éléments de réflexion sur les recherches en cours et à mettre en oeuvre, en particulier les recherches susceptibles de mieux contrôler et anticiper l’épidémie et son évolution, et de fournir des possibilités de traitement ou de prévention. (lire la suite…)

Background: Plasmodium falciparum outbreaks can occur in the coastal area of French Guiana, where the population is essentially non-immune. Two sporadic outbreaks were observed, including one with severe malaria cases. To characterize these outbreaks and verify previous observations of specific genotype characteristics in severe malaria in this area, all cases from each outbreak were studied.

Methods: P. falciparum genotypes for six genetic loci were determined by PCR amplification from peripheral blood parasites. The msp1/block2 and msp2 genotypes were determined by DNA sequencing. Microsatellite and varD genotyping was based on size polymorphism and locus-specific amplification. (lire la suite…)